The Mechanism of Proteinuria

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Mechanism of Proteinuria

Intraperitoneal administration of bovine albumin sharply increases glomerular permeability to hemoglobin in the rat kidney. In addition, bovine albumin "saturates" the tubular absorption mechanism and inhibits the tubular absorption of subsequently administered hemoglobin. Egg white, ovalbumin, and ovomucoid, in contrast, do not produce significant changes in glomerular permeability to hemoglob...

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Studies on the Mechanism of Proteinuria.

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Studies on the Mechanism of Experimental Proteinuria

When renin is administered intramuscularly to the rat, massive proteinuria occurs without a significant elevation of mean arterial blood pressure. The intravenous administration of renin to normal rats results in a great increase in urinary protein excretion. This response to renin is abolished by bilateral adrenalectomy. While the adrenalectomized rat fails to respond to intravenous renin with...

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Studies on the Mechanism of Experimental Proteinuria Induced by Renin

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1949

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.35.4.194